| Mississippi explorer |
| Pacific Ocean discoverer |
| Mississippi cargo item |
| A Mississippi source |
| Mississippi's state flower |
| Italian discoverer of six comets |
| Comet co-discoverer who shares his name with a father-and-son acting pair |
| Mississippi politico Trent |
| Banned pesticide whose discoverer won a Nobel Prize |
| Letter prevalent in Mississippi? |
| A foursome in Mississippi |
| Radium co-discoverer |
| A lot of Mississippi? |
| Alabama, Georgia, Mississippi, etc. |
| Mississippi triangle |
| One of a Mississippi quartet |
| Blues originated in Mississippi |
| A source of the Mississippi |
| Comet co-discoverer Hale |
| Explorer who claimed the Mississippi Basin for France |
| Mississippi discoverer |
| Discoverer of the Marianas: 1521 |
| Mississippi Delta feature |
| Nuclear fission co-discoverer Otto |
| Radium discoverer |
| Longtime Mississippi politico |
| Sandwich Islands discoverer |
| City at the Ohio-Mississippi junction |
| TNT discoverer, tocohorts |
| Mississippi tributary in Mississippi |