| Computer pioneer Lovelace (woo-hoo, women in tech!) |
| Autosuggestion pioneer: 1857–1926 |
| Electric guitar pioneer Fender |
| Pioneering underground publication of the 1960s |
| Tycoon who was reputedly the first person in New York City to own an automobile |
| Ambient pioneer Brian |
| Photography pioneer Louis |
| Pioneering child care author |
| Ambient music pioneer who composed the "Microsoft Sound" for Windows 95: 2 wds. |
| Pharmaceutical pioneer Lilly |
| Aspirin pioneer Hoffmann |
| Abstract art pioneer Jean |
| Massage therapy pioneer Ida |
| Part of an automobile |
| Automobile pioneer Gottlieb |
| Automobile |
| Agricultural pioneer |
| Ambient music pioneer |
| Pioneering web portal |
| Ancient automobile |
| Automobile framework |
| Antiseptic surgery pioneer |
| Pioneer 10 or Voyager 1 |
| A nice Reliant automobile," according to the Barenaked Ladies |
| Computing pioneer Lovelace |
| Genre pioneered by Miles Davis |
| French auto pioneer |
| Swedish automobile |
| Optical products pioneer |
| Computing pioneer Charles |