| Popular game in Old West saloons |
| Mississippi explorer |
| 2002 space western TV series created by Joss Whedon |
| Miss Piggy's favorite word |
| A miss's equivalent |
| ___-air missile |
| #1 song between Phil Collins's "Groovy Kind of Love" and The Escape Club's "Wild Wild West" (1988 wasn't good for music, apparently) |
| Certain missiles, for short |
| Clinic of Midwest |
| 1959-1973 western series that starred Lorne Greene |
| Southwestern promenade |
| A missing pencil may be behind one |
| Midwest university with 23 team wrestling championships |
| Agatha's Miss Jane |
| Valentine misspelling |
| ___-Town (Midwest city's nickname) |
| Pub missile |
| Arid expanse of western Asia |
| Admissions |
| A Midwest time: Abbr. |
| Midwest region |
| All of Me" singer who sang backup for Alicia Keys and Kanye West: 2 wds. |
| Miss Marple finds them |
| Weird Al" Yankovic single about a nuclear holocaust during the holidays, which contains the line "...underneath the missile-toe |
| Alan who played a senator on "The West Wing |
| Cy Young's missiles |
| Me?," to Miss Piggy |
| Pointed missile |
| Activating, as a missile |
| City north-northwest of Oklahoma City |