| Adam and Eve's oldest |
| According to the Bible, the seventh-oldest man at 905 years young |
| Pierre's oldest son |
| From the Philippines oldest Spanish town |
| Israel's oldest daily newspaper |
| Home of the oldest continuously functioning university in the Americas |
| Ringo's oldest son |
| A day's coldest temperature |
| Isaac's boorish kid |
| One of Isaac's twins |
| Napoleon's oldest sister. |
| Bombeck who wrote "Motherhood: The Second Oldest Profession |
| Isaac's hairy firstborn |
| Oldest of the Bridges |
| Isaac's eldest |
| Ben's oldest son on "Bonanza |
| Africa's oldest democracy |
| Isaac's eldest son |
| Highbrow monthly that's the second-oldest continuous publication in the U.S. |
| Gru's oldest adoptive daughter in "Despicable Me |
| Africa's first and oldest republic |
| Africa's oldest independent country |
| The oldest and strongest emotion of mankind," per H. P. Lovecraft |
| Isaac's firstborn |
| Oldest of a trio of comedic brothers |
| Oldest of the "Animaniacs" siblings |
| Isaac's hirsute son |
| The hairier of Isaac's sons |
| Daily temperature's coldest extreme |
| Adam and Eve's oldest child |